〔摘 要〕 目的：对单侧鼻腔鼻窦病变特点进行分析以期更好地对单侧鼻窦病变进行临床管理。 方法：回顾性分析 2018 年 1 月至 2021 年 12 月福建医科大学附属龙岩第一医院收治的 299 例单侧鼻腔鼻窦病变患者临床资料，分析患者主要 临床表现、鼻腔鼻窦病变检出类型、临床诊断及治疗方法及预后情况。 结果：无典型临床症状者占 5.69 %，伴明显临床症 状者占 94.31 %。慢性鼻窦炎、鼻腔鼻窦内翻性乳头状瘤及鼻窦真菌病检出率最高。全部患者术前经鼻内镜检查、鼻窦检 查并结合患者临床症状和病史进行病情诊断，接受磁共振成像（MRI）检查者占 50.84 %，接受鼻腔肿物活检病理检查者占 39.13 %，术前明确诊断者占77.26 %，术中及术后方明确诊断者占22.74 %。保守治疗者占6.69 %，接受手术治疗者占93.31 %。 并发症总发生率达 2.34 %。随访结果表明复发率达 1.00 %，经对症治疗后恢复良好。 结论：单侧鼻窦病变性质复杂及疾病 类型丰富，以慢性鼻窦炎、鼻腔鼻窦内翻性乳头状瘤及鼻窦真菌病最为常见，术前诊断应完善辅助检查，提高诊断准确率， 有助于临床医生有针对性地制定治疗方案，可提高临床治疗效果，改善患者预后。
〔Abstract〕 Objective To analysis the unilateral nasal cavity and sinus disease for improve the diagnose and management of the unilateral sinus disease. Methods The clinical data of 299 patients with unilateral nasal and sinus disease admitted to Longyan First Hospital Affiliated to Fujian Medical University from January 2018 to December 2021 were retrospectively analyzed, and the main clinical manifestations, detected types of nasal and sinus disease, clinical diagnosis, treatment and prognosis of the patients were analyzed. Results 5.69 % of patients had no typical clinical symptoms and 94.31 % of patients had obvious clinical symptoms. The detection rates of chronic sinusitis, inverted papilloma of nasal cavity and sinusoidal mycosis were the highest. All patients were diagnosed by nasal endoscopy and sinus examination before operation, combined with clinical symptoms and medical history of patients. 50.84 % of patients received magnetic resonance imaging (MRI) examination, 39.13 % of patients received nasal mass biopsy and pathological examination, 77.26 % of patients received definite diagnosis before operation, and 22.74 % of patients received definite diagnosis during and after operation. Conservative treatment accounted for 6.69 %, and surgical treatment accounted for 93.31 %. The total complication rate was 2.34 %. The follow-up results showed that the recurrence rate reached 1.00 %, and the recovery was good after symptomatic treatment. Conclusion Unilateral sinus disease are complex in nature and rich in disease types, with chronic sinusitis, inverted papilloma of nasal cavity and sinusoidal sinus and sinusoidal mycosis being the most common. Preoperative diagnosis should be improved by auxiliary examination to improve the diagnostic accuracy, which is helpful for clinicians to make targeted treatment plans, improve clinical treatment effect and improve patient prognosis.