脉通凝汤联合低分子肝素钙预防髋膝 关节置换术后 DVT 形成的效果
作者:
作者单位:

作者简介:

尚继军,男,主治医师,主要研究方向是髋膝部创伤、关节。

通讯作者:

中图分类号:

R 61

基金项目:

河南省中医药科学研究专项课题(20–21ZY1061)


Effect of Maitongning Decoction Combined with Low Molecular Weight Heparin Calcium on Preventing DVT after Hip and Knee Replacement
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    摘 要目的:探讨脉通凝汤联合低分子肝素钙预防髋膝关节置换术后下肢深静脉血栓(DVT)形成的效果。 方法:选择 2021 年 1 月至 2022 年 12 月在郑州德仁骨科医院接受髋膝关节置换术治疗的 86 例患者,按随机对照原则分对照组和 观察组,每组 43 例。对照组术后给予低分子肝素钙,观察组在对照组基础上联合脉通凝汤治疗,均给予 10 d 治疗。比较两 组患者凝血功能、血液流变学指标、DVT 与不良反应的发生率。 结果:治疗后,观察组患者凝血酶原时间(PT)、活化部 分凝血活酶时间(APTT)、凝血酶时间(TT)均长于对照组,纤维蛋白原(FIB)及 D– 二聚体(D–D)水平均低于对照组, 差异具有统计学意义(P < 0.05);治疗后,观察组患者全血高切黏度(HS)、全血低切黏度(LS)、血浆黏度(PV)均 低于对照组,差异具有统计学意义(P < 0.05);两组患者不良反应发生率比较,差异无统计学意义(P > 0.05);观察组 患者 DVT 发生率低于对照组,差异具有统计学意义(P < 0.05)。 结论:脉通凝汤联合低分子肝素钙可有效预防髋膝关节 置换术后 DVT 形成,改善凝血功能及血液流变学指标,且未增加不良反应。

    Abstract:

    AbstractObjective To explore the effect of Maitongning decoction combined with low molecular weight heparin calcium in preventing the formation of deep venous thrombosis (DVT) of lower limbs after hip and knee replacement. Methods A total of 86 patients receiving hip and knee replacement in Zhengzhou Deren Orthopaedic Hospital from January 2021 to December 2022 were selected and divided into a control group and an observation group according to the principle of randomized control, with 43 cases in each group. The control group was given low molecular weight heparin calcium after operation, and the observation group was treated with Maitongning decoction for 10 days. The incidence of coagulation function, hemorheology, DVT and adverse reactions were compared between the two groups. Results After treatment, the prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) in the observation group were all longer than those in the control group, while the levels of fibrinogen (FIB) and D-dimer (D-D) in the observation group were lower than those in the control group, with statistical significance (P < 0.05). After treatment, the levels of whole blood high tangential viscosity (HS), whole blood low tangential viscosity (LS) and plasma viscosity (PV) in the observation group were lower than those in the control group, and the differences were statistically significant (P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05). The incidence of DVT in the observation group was lower than that in the control group, and the difference was statistically significant (P < 0.05). Conclusion Maitongning decoction combined with low molecular weight heparin calcium can effectively prevent the formation of DVT after hip and knee replacement, improve coagulation function and hemorheology, and do not increase adverse reactions.

    参考文献
    相似文献
    引证文献
引用本文
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2023-05-14
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2023-10-26
  • 出版日期:
重要通知

近期有不法分子冒充我刊名义给作者打电话或发邮件,提示关于“知网、万方、维普等数据调整通知”或其他莫名原由,要求添加微信。我刊在此声名:杂志社与作者沟通方式为电话与邮件(在杂志社网站的“联系我们”下拉菜单,或者网站最下端信息栏可以查到),不会要求作者添加微信。另,此网站为本刊唯一官方网站,其他均为假冒网站。望广大作者提高警惕,谨防上当。谢谢配合! 《深圳中西医结合杂志》编辑部

关闭