基于 “ 四海 ” 理论探索雷火灸联合揿针治疗 肺脾气虚型过敏性鼻炎的效果
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王芹,女,副主任护师,主要从事中医护理工作。

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R 246.81

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中山市社会公益与基础研究项目(2021B1070)


Exploring the Effect of Thunder-Fire Moxibustion Combined with Press Needle in Treating Allergic Rhinitis of Lung Spleen Deficiency Syndrome Based on the "Four Seas" Theory
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    摘要:

    摘 要目的:基于 “ 四海 ” 理论探索雷火灸联合揿针治疗肺脾气虚型过敏性鼻炎(AR)的效果及对免疫功能的 影响。 方法:选取 40 只 8 月龄大鼠,10 只为对照组,其余 30 只采用后肢跟腱切除法造模。造模后平均分为模型组、 电针组和塞来昔布组,8 周后取材。肉眼和光镜下观察各组大鼠膝软骨组织形态学变化,分别通过 Moran 评分、Mankin 评 分判定软骨病变程度;用 Western blot 法分别检测各组大鼠软骨 TLR4、NF–κBp65 磷酸化蛋白(p–NF–κBp65)以及白细胞 介素 –6(IL–6)、肿瘤坏死因子 –α(TNF–α)含量变化。 结果:治疗后,观察组患者鼻炎症状得分、免疫球蛋白(Ig)E 水平低于对照组, 差异具有统计学意义(P < 0.05)。治疗后,观察组患者鼻黏膜指征评分低于对照组、分化抗原(CD)4+ 水平明显 高于对照组,差异具有统计学意义(P < 0.05)。观察组患者复发率明显低于对照组,差异具有统计学意义(P < 0.05)。 结论:对肺脾气虚型 AR 患者实施以 “ 四海 ” 理论为指导的雷火灸联合揿针治疗,可以显著改善其临床症状,并且复 发率较低。

    Abstract:

    AbstractObjective To explore the effect of thunder-fire moxibustion combined with press needle in the treatment of allergic rhinitis (AR) of lung spleen deficiency syndrome based on the theory of "Four Seas" and its effect on immune function. Methods From May 2022 to August 2023, 100 patients with AR of lung spleen deficiency syndrome in Zhongshan Hospital of Traditional Chinese Medicine were selected as the research objects. They were randomly divided into an observation group (50 cases) and a control group (50 cases). The control group was treated with conventional Western medicine, and the observation group was treated with thunder-fire moxibustion combined with press needle by the traditional "Four Seas" theory. The clinical efficacy of the two groups of patients was compared. Results After treatment, the rhinitis symptom score and the level of immunoglobulin (Ig) E of the observation group were lower than those of the control group, and the differences were statistically significant (P < 0.05). After treatment, the nasal mucosa indication score of the observation group was lower than that of the control group, and the level of cluster of differentiation (CD) 4+ was significantly higher than that of the control group, and the differences were statistically significant (P < 0.05). The recurrence rate of the observation group was significantly lower than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion Thunder-fire moxibustion combined with press needle treatment guided by "Four Seas" theory can significantly improve the clinical symptoms of AR patients with lung spleen deficiency syndrome, and the recurrence rate is relatively low.

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  • 收稿日期:2023-12-23
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  • 在线发布日期: 2024-06-28
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