养心益气通脉汤联合美托洛尔治疗冠心病 合并快速型心律失常临床研究
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丰俊鹏,男,主治中医师,主要研究方向是心血管疾病的诊治。

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R 541

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河南省中医药传承与创新人才工程(仲景工程)中医药拔尖人才项目(豫卫中医函〔2021〕15 号)


Effect of Yangxin Yiqi Tongmai Decoction Combined with Metoprolol on Coronary Heart Disease Complicated with Tachyarrhythmia
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    摘要:

    摘 要目的:探讨养心益气通脉汤联合美托洛尔治疗冠心病(CHD)合并快速型心律失常的效果。 方法:选取在平 顶山市中医医院 2020 年 7 月至 2022 年 12 月期间诊治的 76 例 CHD 合并快速型心律失常患者,按照随机数字表法分为对照 组和观察组,每组 38 例。对照组患者按照常规治疗方案给予美托洛尔治疗,观察组患者给予养心益气通脉汤联合美托洛尔 治疗,比较两组患者临床疗效、中医证候积分、血液流变学指标、不良反应发生情况。 结果:观察组患者总有效率高于对照组, 差异具有统计学意义(P < 0.05);治疗后,观察组患者各症状积分低于对照组,差异具有统计学意义(P < 0.05);治疗 后,观察组患者血浆黏度、纤维蛋白原水平低于对照组,差异具有统计学意义(P < 0.05);两组患者不良反应发生率比较, 差异无统计学意义(P > 0.05)。 结论:养心益气通脉汤联合美托洛尔应用于 CHD 合并快速型心律失常患者的治疗,可以 有效提高其临床治疗效果,改善临床症状和血液流变学情况,且不会增加不良反应的发生。

    Abstract:

    AbstractObjective To investigate the effect of Yangxin Yiqi Tongmai decoction combined with metoprolol on coronary heart disease (CHD) complicated with tachyarrhythmia. Methods A total of 76 patients with CHD and tachyarrhythmia diagnosed and treated in Pingdingshan Hospital of Traditional Chinese Medicine from July 2020 to December 2022 were selected and divided into a control group and an observation group according to random number table method, with 38 cases in each group. The control group was treated with metoprolol according to the conventional treatment plan, and the observation group was treated with Yangxin Yiqi Tongmai decoction combined with metoprolol. The clinical efficacy, traditional chinese medicine syndrome score, hemorheology index and occurrence of adverse reactions were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P < 0.05). After treatment, the score of symptoms in the observation group was lower than that in the control group, and the difference was statistically significant (P < 0.05), After treatment, the levels of plasma viscosity and fibrinogen levels in the observation group were lower than those in the control group, with statistical significance (P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion Yangxin Yiqi Tongmai decoction combined with metoprolol in the treatment of CHD patients with tachyarrhythmia can effectively improve the clinical treatment efficiency, improve clinical symptoms and hemorheology, and will not increase the occurrence of adverse reactions.

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  • 收稿日期:2023-12-11
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  • 在线发布日期: 2024-06-28
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