〔摘 要〕 目的：探究桃红四物汤加减对手部软组织缺损患者血管危象、皮瓣存活率及手指总活动度的影响。 方法：选择南阳市中医院 2020 年 3 月至 2022 年 12 月收治的 72 例手部软组织缺损手术患者，按随机数字表法分成对照组和 观察组，各 36 例。对照组患者给予常规西药治疗，观察组患者给予桃红四物汤加减治疗，比较两组患者凝血指标［活化部 分凝血活酶时间（APTT）、凝血酶原时间（PT）］、皮瓣情况［肿胀程度、视觉模拟评分法（VAS）、血管危象发生率］、 皮瓣存活率和手指总活动度。 结果：治疗后，观察组患者的 APTT、PT 水平高于对照组，差异具有统计学意义（P ＜ 0.05）； 观察组患者的血管危象发生率为 11.11 %，低于对照组的 33.33 %，差异具有统计学意义（P ＜ 0.05）；治疗后，观察组患 者肿胀程度、VAS 评分均低于对照组，差异具有统计学意义（P ＜ 0.05）；观察组患者的皮瓣存活率、手指总活动度优良 率均高于对照组，差异具有统计学意义（P ＜ 0.05）。 结论：桃红四物汤加减对手部软组织缺损手术患者的治疗，能有效 改善其凝血功能和皮瓣情况，降低血管危象发生率，提高皮瓣存活率和手指总活动度优良率。
〔Abstract〕 Objective To investigate the effects of Taohong Siwu Decoction on vascular crisis, survival rate of skin flap and total range of motion of fingers in patients with soft tissue defect of hand. Methods A total of 72 patients with hand soft tissue defect surgery admitted to Nanyang Hospital of Traditional Chinese Medicine from March 2020 to December 2022 were selected and divided into a control group and an observation group according to random number table method, with 36 cases in each group.The control group was treated with conventional western medicine, and the observation group was treated with Taohong Siwu Decoction. The coagulation indexes [activated partial thromboplastin time (APTT), prothrombin time (PT)], skin flap conditions [swelling degree, visual analogue scale (VAS), incidence of vascular crisis], skin flap survival rate and total finger motion were compared between the two groups. Results After treatment, the levels of APTT and PT in the observation group were higher than those in the control group, the differences were statistically significant (P < 0.05). The incidence of vascular crisis in the observation group was 11.11 %, lower than 33.33 % in the control group, the difference was statistically significant (P < 0.05). After treatment, the scores of swelling degree and VAS in the observation group were lower than those in the control group, the differences were statistically significant (P < 0.05). The skin flap survival rate and the excellent and good rate of total finger motion in the observation group were higher than those in the control group, and the differences were statistically significant (P < 0.05). Conclusion Taohong Siwu Decoction can effectively improve the coagulation function and skin flap condition, reduce the incidence of vascular crisis, increase the skin flap survival rate and the excellent and good rate of total finger motion in the treatment of patients with hand soft tissue defect.