〔摘 要〕 目的：分析重症监护室（ICU）患者发生尿路感染（UTI）的危险因素，并制定相应的护理对策。 方法：收集 2020 年 5 月至 2023 年 5 月期间收治于开封市中心医院 ICU 发生 UTI 的 40 例患者临床资料并纳入发生组，另选取同 期收治于 ICU 未发生 UTI 的 40 例患者临床资料纳入未发生组，研究人员收集并查阅患者相关资料，自拟一般资料问卷表， 记录患者相关信息，经 logistic 回归分析 ICU 患者发生 UTI 的危险因素并制定护理对策。 结果：发生组患者年龄大于未发 生组，尿路有创操作史、留置尿管时间≥ 5 d、插管次数＞ 3 次、合并糖尿病占比均高于未发生组，差异具有统计学意义 （P ＜ 0.05）；经 logistic 回归分析结果显示，年龄大、尿路有创操作、留置尿管时间≥ 5 d、插管次数＞ 3 次、合并糖尿 病均为 ICU 患者发生 UTI 的危险因素。 结论：ICU 患者发生 UTI 的危险因素为患者年龄大、尿路有创操作史、留置尿管时 间长、插管次数多、合并糖尿病，临床应重点关注上述因素，实施对应干预措施，以降低 UTI 发生风险。
〔Abstract〕 Objective To explore the value of integrated management intervention combined with sacubitril valsartan in the clinical treatment of patients with heart failure and renal insufficiency. Methods The clinical data of 40 patients with UTI in the ICU of Kaifeng Central Hospital from May 2020 to May 2023 were collected and included in the occurrence group, while the clinical data of 40 patients without UTI in the ICU during the same period were selected and included in the non-occurrence group. The researchers collected and consulted the relevant data of patients, made a general data questionnaire, recorded the relevant information of patients, analyzed the risk factors of UTI in ICU patients by logistic regression and formulated nursing countermeasures. Results The patients in the occurrence group were older than those in the non-occurrence group, and the proportion of patients with urinary tract invasive operation history, indwelling catheter time ≥ 5 days, intubation times > 3 times and diabetes mellitus was higher than that in the non-occurrence group, with statistical significance (P < 0.05). logistic regression analysis showed that age, invasive operation of urinary tract, indwelling catheter time ≥ 5 days, intubation times > 3 times and diabetes mellitus were all risk factors for UTI in ICU patients. Conclusion The risk factors for UTI in ICU patients are old age, a history of invasive urinary tract operation, long catheter retention time, multiple intubation times, and diabetes mellitus. Attention should be paid to these factors, and corresponding interventions should be implemented to reduce the risk of UTI.