〔Abstract〕 Objective To explore the value of integrated management intervention combined with sacubitril valsartan in the clinical treatment of patients with heart failure and renal insufficiency. Methods The clinical data of 40 patients with UTI in the ICU of Kaifeng Central Hospital from May 2020 to May 2023 were collected and included in the occurrence group, while the clinical data of 40 patients without UTI in the ICU during the same period were selected and included in the non-occurrence group. The researchers collected and consulted the relevant data of patients, made a general data questionnaire, recorded the relevant information of patients, analyzed the risk factors of UTI in ICU patients by logistic regression and formulated nursing countermeasures. Results The patients in the occurrence group were older than those in the non-occurrence group, and the proportion of patients with urinary tract invasive operation history, indwelling catheter time ≥ 5 days, intubation times > 3 times and diabetes mellitus was higher than that in the non-occurrence group, with statistical significance (P < 0.05). logistic regression analysis showed that age, invasive operation of urinary tract, indwelling catheter time ≥ 5 days, intubation times > 3 times and diabetes mellitus were all risk factors for UTI in ICU patients. Conclusion The risk factors for UTI in ICU patients are old age, a history of invasive urinary tract operation, long catheter retention time, multiple intubation times, and diabetes mellitus. Attention should be paid to these factors, and corresponding interventions should be implemented to reduce the risk of UTI.