Abstract:〔Abstract〕 Objective To investigate the effect of different concentration of ropivacaine epidural analgesia on parturients. Methods Eighty primiparas who underwent painless delivery in the First Affiliated Hospital of Henan University of Chinese Medicine from January 2019 to January 2022 were retrospectively selected as the research objects. Among them, 34 patients received low concentration of ropivacaine hydrochloride for epidural labor analgesia, which was the low concentration group. 46 cases were treated with ropivacaine hydrochloride ,which was the high concentration group. Clinical data such as labor time, uterine contraction, pain and delivery outcome were collected. The first stage of labor, the second stage of labor, the third stage of labor and the total labor time of the two groups were compared. The duration and interval of uterine contractions were compared between the two groups before analgesia (T1), 4 cm dilation of the uterine orificum (T2), complete dilation of the uterine orificum (T3), and visual analog scale (VAS) scores before analgesia, 10 min, 30 min and 1 h after analgesia. The amount of postpartum blood loss, the amount of oxytocin, urethral catheterization during delivery and the rate of cesarean section were compared between the two groups. Results There was no significant difference in the first stage of labor, second stage of labor, third stage of labor and total stage of labor between the two groups (P > 0.05) . The statistical results of uterine contractions showed that the duration of T2 and T3 in the low concentration group was longer than those in the high concentration group, the differences were statistically significant (P < 0.05), while the interval time was shorter than that in the high concentration group, the difference was statistically significant (P < 0.05). At 10 min, 30 min and 1 h after analgesia, VAS scores in the low concentration group were higher than those in the higher concentration group, and the differences were statistically significant (P < 0.05). The amount of oxytocin in the low concentration group was lower than that in the high concentration group, and the difference was statistically significant (P < 0.05). Conclusion Different concentrations of local anesthesia drugs used during epidural labor analgesia have different effects on parturients. Low concentration ropivacaine can greatly reduce the adverse effects on parturients under the premise of guaranteeing the analgesic effect.